Clinical Trial: Three Measures for the Prevention of Carious Lesions in Preschool Children

Study Status: Active, not recruiting
Recruit Status: Unknown status
Study Type: Interventional

Official Title: Study on Children's Dental Caries Prevention and Mechanism

Brief Summary: Analysis different measures preventive effect on carious Lesions incidence and oral microecological system change of preschool children

Detailed Summary: Different caries prevention trials including fluoride vanish, IgY-passive immunotherapy and probiotics lasting 24 months were conducted with a total of 500 children aged 24 to 54 months of age in Lin'an, Zhejiang, China. The trials were cluster— domized .After obtaining parent´s informed consent, preschool children were clinical examinated according to ICDAS-Ⅱ and microbiological tested of saliva at baseline, 1m, 6m, 12m, 18m and 24m. To find the differences of caries incidence and oral microecology change in four groups, dmfs will be assessed and saliva will be analysed in experiment.
Sponsor: Zhejiang University

Current Primary Outcome: The number of new cavitated or incipient carious lesion [ Time Frame: 24 months after first visit ]

To determine whether preschool children that only with caregiver behavior education have more new caries lesion than those taken some caries preventive measures by differences in dmfs（decay，missing，filling teeth surfaces） index after 24 months dental exams.


Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Zhejiang University

Dates:
Date Received: January 8, 2015
Date Started: April 2013
Date Completion: June 2015
Last Updated: January 13, 2015
Last Verified: January 2015