Clinical Trial: Intravitreal Avastin in Proliferative Retinopathies

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Intravitreal Injections With Avastin in Proliferative Retinopathies Related to the Production of VEGF Having Different Causes

Brief Summary: The study intends to assess the effect of Avastin injections in different proliferative retinopathies due to different causes

Detailed Summary:

Proliferative retinopathies due to different causes represent important causes for the visual acuity loss. Conventional treatments may sometimes improve the visual function, whereas other times, the visual acuity continue to decrease, in spite of all the medical, surgical or laser treatments.

Intravitreal injections with anti-VEGF agents (ex. Avastin for our trial) seem to be an important tool for certain difficult situations in which at the ocular fundus, out of different reasons (advanced age, diabetes mellitus, retinal veins occlusions, etc)new pathologic vessels appear, causing devastating changes in the posterior and anterior segment as well.

Sponsor: Ophthalmological Association Edelweiss

Current Primary Outcome: The following parameters will be assessed in order to evaluate the Avastin effect: visual acuity, lesions's area at the ocular fundus [ Time Frame: one year ]

Original Primary Outcome: Same as current

Current Secondary Outcome: The intraocular pressure will be measured during the whole study in order to assess the possible side effects of Avastin injections [ Time Frame: one year ]

Original Secondary Outcome: Same as current

Information By: Ophthalmological Association Edelweiss

Dates:
Date Received: November 26, 2007
Date Started: July 2007
Date Completion:
Last Updated: July 20, 2011
Last Verified: June 2008