Clinical Trial: Macular Hemorrhage in Myopic Eyes

Study Status: Recruiting
Recruit Status: Unknown status
Study Type: Observational [Patient Registry]

Official Title: Macular Hemorrhage in Myopic Eyes

Brief Summary: Visual impairment in high myopic eyes is mainly due to the different types of myopic maculopathies, such as diffuse or patchy atrophy, lacquer cracks and choroidal neovascularization. Macular hemorrhage was one of those complications. Despite choroidal neovascularization, simple hemorrhage from rupture of Bruch's membrane and choroidal microcirculation is also the cause of hemorrhage. The prognosis of those eyes with simple hemorrhage is generally good. However, some patients had persistently poor vision after the absorption of the hemorrhage. In the literature, the visual prognosis in those patients was reported to be associated with the microstructure change under the optical coherent tomography (OCT) or the presentation of the autofluorescence. The investigators will collect the patients with high myopia and presenting with macular hemorrhage. High resolution OCT and autofluorescence imaging will be used to analyze the change of the microstructure of retina and its correlation with the visual prognosis.

Detailed Summary:
Sponsor: National Taiwan University Hospital

Current Primary Outcome: visual acuity [ Time Frame: 1 year ]

visual acuity during follow up and its correlation to other factors


Original Primary Outcome: Same as current

Current Secondary Outcome: Optical coherence tomography [ Time Frame: 1 year ]

Change of microstructure of the retina and choroid on OCT during follow up


Original Secondary Outcome: Same as current

Information By: National Taiwan University Hospital

Dates:
Date Received: September 12, 2013
Date Started: August 2013
Date Completion: May 2015
Last Updated: April 13, 2014
Last Verified: April 2014