Clinical Trial: Evaluation of Objective Perimetry Using Chromatic Multifocal Pupillometer

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational

Official Title: Objective Perimetry in Normal Subjects,Glaucoma Patients and Retinal Dystrophy Patients

Brief Summary: Objective perimetry can better monitor visual field defects in retinal dystrophy and Glaucoma patients than conventional subjective perimetry. The PLR ( Pupil Light Reflex to short and long wavelength stimuli should be significantly lower compared to healthy participants in areas of visual field defects in retinal dystrophy and Glaucoma patients.

Detailed Summary:

Pupil light reflex (PLR) will be measured by a chromatic multifocal pupillometer in response to short and long wavelength light with small spot stimulus in 76 points of the 30 degree visual field.

A computerized infrared video pupillometer will be used to record changes in pupil diameter in response to short- and long-wavelength stimuli (peak 485 nm and 620 nm, respectively) presented by 76 LEDs, 1.8mm spot size, at light intensities of 10-3000 cd/m2 and duration of 1-3 sec at different points of the 30 degree visual field

Sponsor: Sheba Medical Center

Current Primary Outcome: PLR response amplitude and latency [ Time Frame: single visit ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Sheba Medical Center

Dates:
Date Received: December 12, 2013
Date Started: December 2013
Date Completion: December 2018
Last Updated: January 1, 2017
Last Verified: January 2017