Clinical Trial: Effects of Transcranial Direct Current Electrical Stimulation on the Recovery of Ideomotor Apraxia of the Upper Limbs

Study Status: RECRUITING
Recruit Status: RECRUITING
Study Type: INTERVENTIONAL

Official Title: Effects of Transcranial Direct Current Electrical Stimulation (tDCS) on the Recovery of Ideomotor Apraxia of the Upper Limbs in Patients With Acute Stroke

Brief Summary: Limbs apraxia is a motor disorder whose characteristic is the inability or difficulty to perform intentional movements of the limbs (gestures), most frequently involving the upper limbs.
Recent literature indicated promising effects of transcranial direct current stimulation (tDCS) in the recovery of limbs apraxia, showing that, in stroke patients, excitatory anodal tDCS over left inferior parietal lobe (IPL) may improve limb apraxia.
Despite this encouraging evidence, the need for larger well powered and sham-controlled clinical trials has also been identified.
For these reasons, the objective of this study is to investigate the effects of tDCS application on the left posterior parietal cortex, associated with the treatment for apraxia made by Smania et al. in 2000, on the recovery of the upper limbs ideomotor apraxia in patients with left brain lesion of vascular origin.

Detailed Summary:
Sponsor: Clinica di Riabilitazione Toscana Spa

Current Primary Outcome:

It consists of 24 imitation tests carried out with the fingers, the hand and the limb homolateral to the lesion.

Each gesture is presented up to three times if the production is incorrect, and receives a score of 3 to 0 depending on whether the copy is correct the first, the second, the third time, or never.
The test includes 24 gestures, 12 symbolic and 12 non-symbolic, for a total score of 72.
Application of the test to over 200 normal subjects showed that the diagnosis of apraxia can be made reliably when the score drops below 53, it's probable, but not certain, for a score between 53 and 62, and it's excluded when the score is greater than 62.

Original Primary Outcome:

It consists of 24 imitation tests carried out with the fingers, the hand and the limb homolateral to the lesion.

Each gesture is presented up to three times if the production is incorrect, and receives a score of 3 to 0 depending on whether the copy is correct the first, the second, the third time, or never.
The test includes 24 gestures, 12 symbolic and 12 non-symbolic, for a total score of 72.
Application of the test to over 200 normal subjects showed that the diagnosis of apraxia can be made reliably when the score drops below 53, it's probable, but not certain, for a score between 53 and 62, and it's excluded when the score is greater than 62.

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Clinica di Riabilitazione Toscana Spa

Dates:
Date Received: February 15, 2022
Date Started: February 02, 2022
Date Completion: March 01, 2024
Last Updated: September 06, 2023
Last Verified: September 01, 2023