Clinical Trial: Effects of 2 Different Duration of Albendazole Therapy in Patients With Neurocysticercosis in Brain ≤ 5 Lesions on CT

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: A Clinical Trial to Study the Effects of Two Different Duration of Same Drug Albendazole in Patients With Neurocysticercosis in Brain ≤ 5 Lesions on CT Scan Head at

Brief Summary: Comparing the effect of two different duration of same drug albendazole in patients with Neurocysticercosis less than or equal to 5 lesions on CT head at the end of 6 months.

Detailed Summary: The trial will be comparing the effectiveness of short and long duration of albendazole ie 7 and 28 days therapy in patients with parenchymal neurocysticercosis in terms of complete resolution or calcification of cyst on CT head at the end of 6 months after starting albendazole
Sponsor: All India Institute of Medical Sciences, New Delhi

Current Primary Outcome: Number of cyst resolved/ calcified completely after therapy. Resolution or calcification of cyst assessed on CT head at the end of 6 months after starting albendazole [ Time Frame: 1 year ]

A randomized open labeled control clinical trial to compare the radiological outcome of 7 days versus 28 days albendazole therapy along with steroid in patients with parenchymal neurocysticercosis with lesion load < 5


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Frequency of seizure occurrence [ Time Frame: 1 year ]
    A randomized open labeled control clinical trial to compare the radiological outcome of 7 days versus 28 days albendazole therapy along with steroid in patients with parenchymal neurocysticercosis with lesion load < 5
  • Frequency of occurrence of other symptoms attributable to Neurocysticercosis [ Time Frame: 1 year ]
    A randomized open labeled control clinical trial to compare the radiological outcome of 7 days versus 28 days albendazole therapy along with steroid in patients with parenchymal neurocysticercosis with lesion load < 5
  • Frequency of occurrence of side effects of albendazole [ Time Frame: 1 year ]
    A randomized open labeled control clinical trial to compare the radiological outcome of 7 days versus 28 days albendazole therapy along with steroid in patients with parenchymal neurocysticercosis with lesion load < 5


Original Secondary Outcome: Same as current

Information By: All India Institute of Medical Sciences, New Delhi

Dates:
Date Received: May 5, 2014
Date Started: March 2014
Date Completion:
Last Updated: December 31, 2015
Last Verified: December 2015