Clinical Trial: Clinical Trial of Pulmonary Cryptococcosis in China

Study Status: Enrolling by invitation
Recruit Status: Enrolling by invitation
Study Type: Observational [Patient Registry]

Official Title: Multi-center Clinical Trial of Pulmonary Cryptococcosis in China

Brief Summary: The purpose of the study:1.Improve the understanding of the risk factors of pulmonary cryptococcosis;2.Improve the awareness of pulmonary cryptococcosis clinical and imaging manifestations;3.Grasp pulmonary cryptococcosis patients of clinical and imaging manifestations in different conditions;4.Learn about antibacterial activity of antifungal drugs for cryptococcosis in China.

Detailed Summary:

  1. Patients corresponding to inclusion criteria and obtaining informed consent are included in the research in department of respiration ward in cooperative hospitals.
  2. Relevant case report forms are created in this study.
  3. Basic information such as age,weight and height is recorded in selected cases.Clinical manifestations,risk factors,laboratory examination,imaging examination,etiological examination and histopathological examination are also recorded in selected cases by case report forms.In addition,antifungal treatment is recorded including name,dose,time of starting treatment and terminate treatment.Causes of terminate treatment and curative effect evaluation should be analysed.
  4. Statistical analysis.

Sponsor: Zhixin Liang

Current Primary Outcome: differences in clinical manifestations of pulmonary cryptococcosis [ Time Frame: 30 days ]

Methods including laboratory examination(routine blood test),imaging examination(chest CT),scoring system(APACHE II score)


Original Primary Outcome: Same as current

Current Secondary Outcome: treatment of pulmonary cryptococcosis [ Time Frame: 30 days ]

Efficacy as measured by recording dose and time of therapy for antifungal agents


Original Secondary Outcome: Same as current

Information By: Chinese PLA General Hospital

Dates:
Date Received: December 28, 2014
Date Started: December 2014
Date Completion: December 2017
Last Updated: July 17, 2015
Last Verified: July 2015