Clinical Trial: Effect of Copper Impregnated Textiles on Healthcare Associated Infections and Antibiotic Use

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: Effect of Copper Impregnated Textiles on Healthcare Associated Infections and Antibiotic Use in a Single Intensive Care Unit

Brief Summary: This is a prospective Infection Control study comparing rates of antibiotic usage and infections in the General Intensive Care Unit (GICU) in beds with copper impregnated linens versus regular linens.

Detailed Summary:

One ward of the ICU had copper impregnated linen while the other had regular linen. This included sheets, pillowcases, towels and patient gowns. After the first 23 week period was completed, there was a 3 week washout period. After this, the wards were switched with the first using regular linen and the second using copper impregnated linen.

The investigators followed participants and documented any infections >48 hours after admission to the ICU. The number and days of antibiotics used for the infections were also documented. Using assigned study numbers, the investigators obtained demographic data: age, sex, co-morbid conditions, and admitting diagnosis. All participants were followed daily in the GICU and daily for 48 hours after transfer to the regular floor. Date of discharge will be obtained retrospectively. Infection control (IC) routinely obtains Methicillin Resistant Staphylococcus Aureus (MRSA) nasal swabs on all patients on admission to the GICU, once weekly while in GICU and then again on discharge from the GICU. They monitor the GICU patients for healthcare associated infections (HAI) that meet the National Healthcare Safety Network (NHSN) 146 definitions. The NHSN is a widely used HAI tracking system, and the infections documented included Ventilator associated pneumonia (VAP), Catheter related blood stream infections (CLABSI), catheter associate urinary tract infections (CAUTI) and Clostridium difficile associated diarrhea (CDAD). They also obtain information on decubitus ulcers (bed sores) that develop during hospital stay. Infection control also routinely monitors the isolation of multi-drug resistant bacteria, namely Vancomycin Resistant Enterococci (VRE), Extended Spectrum beta Lactamase producing organisms (ESBL) and Carbapenemase producing enterobacteriaceae (CRE) as well as Multi drug resistant (MDR ) Acinetobacter baumanii from cultures. This abo
Sponsor: Eastern Virginia Medical School

Current Primary Outcome: Antibiotic usage in copper impregnated vs regular linen wards >48 hours after admission to ICU [ Time Frame: Two study periods of 23 weeks each ]

To assess whether the use of copper impregnated linens was associated with decreased use of antibiotics


Original Primary Outcome: Antibiotic usage in copper impregnated vs regulalr linen wards >48 hours after admission to ICU [ Time Frame: Duration of study ]

Our study aims to assess whether the use of copper impregnated linens was associated with decreased use of antibiotics


Current Secondary Outcome:

  • Decrease in clinical infection [ Time Frame: Two study periods of 23 weeks each ]
    To assess whether the copper impregnated linen usage was associated with decrease in the number of clinical infections diagnosed by physicians
  • Decrease in NHSN infection [ Time Frame: Two study periods of 23 weeks each ]
    Secondary measure included whether the copper impregnated linen usage was associated with decrease in the number of NHSN infections as defined by the infection control personnel


Original Secondary Outcome:

  • Decrease in clinical infection [ Time Frame: Duration of study ]
    Secondary measure included whether the copper impregnated linen usage was associated with decrease in the number of clinical infections diagnosed by physicians
  • Decrease in NHSN infection [ Time Frame: Duration of study ]
    Secondary measure included whether the copper impregnated linen usage was associated with decrease in the number of NHSN infections as defined by the infection control personnel (this is done for all ICU patients routinely)


Information By: Eastern Virginia Medical School

Dates:
Date Received: January 27, 2015
Date Started: January 2014
Date Completion:
Last Updated: August 4, 2015
Last Verified: August 2015