Clinical Trial: A Multi-centre, Double-blinded, Randomized, Placebo-controlled Trial on the Efficacy and Safety of Lopinavir / Ritonavir Plus Ribavirin in the Treatment of Severe Acute Respiratory Syndrome
Study Status: Completed
Recruit Status: Unknown status
Study Type: Interventional
Official Title: A Multi-centre, Double-blinded, Randomized, Placebo-controlled Trial on the Efficacy and Safety of Lopinavir / Ritonavir Plus Ribavirin in the Treatment of Severe Acute Respirato
Brief Summary: The study aims to examine whether the combination of Lopinavir/Ritonavir plus Ribavirin for treatment of severe acute respiratory syndrome (SARS) is superior to placebo.
Detailed Summary:
Sponsor: Hospital Authority, Hong Kong
Current Primary Outcome: Development of severe SARS [ Time Frame: Any time during the acute illness ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Adverse events [ Time Frame: Throughout the illness period ]
- SARS-CoV Viral load [ Time Frame: Throughout the illness period ]
- Immunological profile [ Time Frame: Throughout the illness period ]
Original Secondary Outcome: Same as current
Information By: Hospital Authority, Hong Kong
Dates:
Date Received: December 20, 2007
Date Started:
Date Completion:
Last Updated: August 21, 2013
Last Verified: August 2013