Clinical Trial: Observational Study of Corneal Opacities in Adults

Study Status: Completed
Recruit Status: Unknown status
Study Type: Observational

Official Title: Observational Study of Corneal Opacities in Adults

Brief Summary: A prospective observational study on corneal opacities (scar and stromal dystrophy) in adults (n=150) will be conducted at OHSU. The Optovue anterior segment OCT prototype will be used to perform 3-D corneal scans. These scans will be used to assess opacity depth and measure corneal thickness (pachymetry), corneal topography (anterior and posterior), and epithelial thickness maps. The ultrahigh-speed MIT OCT prototypes will also be used when they become available. A comprehensive eye examination, Placido-ring corneal topography, ultrasound pachymetry, and Scheimpflug camera imaging, will be performed for comparison

Detailed Summary:
Sponsor: Oregon Health and Science University

Current Primary Outcome: Identification of suitable subjects [ Time Frame: 2 years ]

The primary goal of this observational study is to identify suitable subjects for the clinical trials of OCT-guided transepithelial PTK and OCT-guided LALAK in adults


Original Primary Outcome: Same as current

Current Secondary Outcome: Validate OCT anterior topography [ Time Frame: 2 years ]

A second goal is to validate OCT anterior topography by comparison with standard Placido-ring corneal topography


Original Secondary Outcome: Same as current

Information By: Oregon Health and Science University

Dates:
Date Received: January 14, 2014
Date Started: June 2011
Date Completion: June 2016
Last Updated: April 21, 2015
Last Verified: April 2015