Clinical Trial: Investigation of Different Scanning Protocols for 3 Dimensional High-resolution Imaging of the Human Cornea With Optical Coherence Tomography (OCT) - A Pilot Study

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Investigation of Different Scanning Protocols for 3 Dimensional High-resolution Imaging of the Human Cornea With Optical Coherence Tomography (OCT) - A Pilot Study

Brief Summary: The aim of the present study is to develop a protocol for optimal corneal 3-dimensional imaging based on measurements in healthy volunteers. For this purpose, a customized ultra-high resolution Spectral Domain OCT will be used. To validate whether the protocol can also be applied in patients with corneal pathologies, for whom it is intended to be used, measurements in these patients will be performed. We propose to obtain images from patients with keratoconus, since this is one of the most frequent causes for corneal transplantations in Europe and from patients with corneal neovascularization which is a major cause of vision loss in several ophthalmic diseases. Based on the obtained measurement protocol, further studies investigating the pathophysiology or treatment success of several corneal pathologies can be planned.

Detailed Summary:
Sponsor: Medical University of Vienna

Current Primary Outcome: Corneal Imaging [ Time Frame: 1 day ]

Development of a measurement protocol for 3 dimensional imaging of the human cornea


Original Primary Outcome: Same as current

Current Secondary Outcome: Imaging of corneal pathologies [ Time Frame: 1 day ]

Application of the protocol in patients with corneal pathologies


Original Secondary Outcome: Same as current

Information By: Medical University of Vienna

Dates:
Date Received: April 26, 2013
Date Started: July 2013
Date Completion: December 2017
Last Updated: November 30, 2016
Last Verified: November 2016