Clinical Trial: Effect of Intravitreal Bevacizumab on Corneal Endothelium

Study Status: Completed
Recruit Status: Unknown status
Study Type: Observational

Official Title: Effect of Intravitreal Bevacizumab on Corneal Endothelium

Brief Summary: To evaluate corneal endothelium cell change after intravitreal Bevacizumab injection

Detailed Summary: Intravitreal Bevacizumab has been used by retinal specialist in treatment many retinal diseases. Although it not approved by FDA for treatment. In many In vitro studies, its showed saftey in the eyes especially for corneal endothelium cells, that important cells to keep cornea clear. This study use Confoscan-Corneal confocal microsope to evaluate corneal endothelium before and after intravitreal Bevacizumab injection in routine retinal disease at 6 month follow up.
Sponsor: Khon Kaen University

Current Primary Outcome: Corneal endothelium cell change after intravitreal Bevacizumab injection [ Time Frame: 6 months ]

Measure the corneal endothelium cell using Confoscan4-Corneal confocal microscope in patient in retinal vascular clinic before and after treat with intravitreal Bevacizumab


Original Primary Outcome: Same as current

Current Secondary Outcome: Assess the complication after intravitreal Bevacizumab injection [ Time Frame: 6 month ]

Original Secondary Outcome: Same as current

Information By: Khon Kaen University

Dates:
Date Received: November 11, 2012
Date Started: August 2011
Date Completion: October 2013
Last Updated: November 11, 2012
Last Verified: November 2012