Clinical Trial: The Consciousness Variation of Deep Brain and Transcranial Magnetic Stimulation for Disorders of Consciousness Patients
Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional
Official Title: The Consciousness Variation of Deep Brain Stimulation (DBS) and Transcranial Magnetic Stimulation (TMS) for Disorders of Consciousness(DOC) Patients in a Large Scale Rando
Brief Summary:
Aims:To explore the consciousness stimulation role of DBS (Deep Brain Stimulation) and TMS (Transcranial Magnetic Simulation) for DOC (Disorders of Consciousness) patients.
Methods:Seventy-five DOC patients will be randomised into three groups: DBS group, TMS group and Control group. Three months after treatments, the result will be analysed and concluded.
Detailed Summary: To explore the consciousness stimulation role of DBS (Deep Brain Stimulation) and TMS (Transcranial Magnetic Stimulation) for DOC (Disorders of Consciousness) patients. Seventy-five DOC patients will be randomised into three groups: DBS group, TMS group and Control group. These patients will be recorded the conscious level and fMRI (functional magnetic resonance imaging) evaluation before treatment of research, and three months later the prognosis were also recorded. Finally, the variation of consciousness, prognosis and fMRI index for three groups will be analysed and compared. Hopefully, there will be a conclusion for these treatments to DOC patients.
Sponsor: Xuehai Wu
Current Primary Outcome: The consciousness variation of DBS and TMS for DOC Patients in a large scale randomised trial (revised-coma recovery scale) [ Time Frame: 3 months ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
Original Secondary Outcome:
Information By: Huashan Hospital
Dates:
Date Received: December 20, 2015
Date Started: November 2015
Date Completion: November 2018
Last Updated: January 28, 2016
Last Verified: January 2016