Clinical Trial: Desloratadine 5, 10 and 20mg in Patients With Cold Urticaria
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Multi-center, Double Blind, Dose Escalating Study to Compare the Effects of 5 mg, 10mg and 20mg of Desloratadine in Patients With Acquired Cold Urticaria (ACU)
Brief Summary: The primary objective of the study is to assess the dosis of DL which is sufficient to inhibit cold urticaria symptoms.
Detailed Summary: A total of 30 patients (male and female) with ACU will be included in this study
Sponsor: Marcus Maurer
Current Primary Outcome: CTTs and CSTTs assessed by TEMPtest 3.0 + urticaria network SOPs [ Time Frame: 6 weeks ]
Original Primary Outcome: Same as current
Current Secondary Outcome: Presence of wheal(s) at 4°C Intensity of pruritus and burning Number and duration of angioedemas QoL as assessed by DLQI Severity of ACU (by ACUSI) [ Time Frame: 6 weeks ]
Original Secondary Outcome: Same as current
Information By: Charite University, Berlin, Germany
Dates:
Date Received: September 29, 2011
Date Started: August 2009
Date Completion:
Last Updated: September 30, 2011
Last Verified: September 2011