Clinical Trial: Sleep, Circadian Rhythms and Cluster Headache

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: Characterisation of Sleep and Circadian Physiology in Individuals With Cluster Headache

Brief Summary:

The purpose of this study is to assess both the sleep and circadian (24-hourly biological rhythms) physiology of people with cluster headache. For sufferers with the episodic form of the disorder this will involve observation at two separate time points, once when experiencing attacks (in-bout) and once when attack free (out-of-bout).

The study will include measurement of basic rest-activity patterns, sleep timing and timing of individual attacks, as well as a more detailed study recording sleep and circadian rhythms under clinical conditions over consecutive nights.

Studying the differences in these processes in single individuals when they are both experiencing and free from attacks might provide insight into the brain mechanisms involved in triggering the bouts of attacks and individual attacks themselves. An improved understanding of this area may help design improved treatment options in future.

Detailed Summary:
Sponsor: University of Surrey

Current Primary Outcome: amplitude and phase of circadian rhythm of melatonin [ Time Frame: 36 hours ]

Original Primary Outcome:

Current Secondary Outcome:

Original Secondary Outcome:

Information By: University of Surrey

Dates:
Date Received: October 4, 2011
Date Started: August 2011
Date Completion:
Last Updated: April 12, 2017
Last Verified: April 2017