Clinical Trial: TWIST Human Gene and Cleft Lips and Palates

Study Status: Terminated
Recruit Status: Terminated
Study Type: Interventional

Official Title: TWIST Human Gene and Cleft Lips and Palates

Brief Summary: This study uses a sequence analysis for TWIST and other craniofacial development genes, among patients presenting with facial clefting.

Detailed Summary:
Sponsor: University Hospital, Strasbourg, France

Current Primary Outcome: to show, among patients displaying facial clefting, the TWIST mutations and the mutation in genes involved with TWIST in craniofacial development [ Time Frame: Not relevant ]

Original Primary Outcome:

  • Can one show, among patients displating facial clefting:
  • -Mutations at TWIST
  • - Mutation at genes, involved with TWIST in cranio-facial development


Current Secondary Outcome: to show, among patients displaying facial clefting and mutations in such genes, possible mutations in the same genes [ Time Frame: Not relevant ]

Original Secondary Outcome: Can one show, among patients displaying facial clefting and mutations at such genes, possible mutations at the same genes

Information By: University Hospital, Strasbourg, France

Dates:
Date Received: September 13, 2005
Date Started: February 2003
Date Completion:
Last Updated: March 26, 2015
Last Verified: March 2015