Clinical Trial: Multicenter Study to Assess the Efficacy of Decitabine in the Treatment of Chronic Myelomonocytic Leukemia

Study Status: Active, not recruiting
Recruit Status: Active, not recruiting
Study Type: Interventional

Official Title: A Phase II Multicenter Open-label Study to Assess the Efficacy of Decitabine in the Treatment of Chronic Myelomonocytic Leukemia

Brief Summary: The study aims to assess the activity of decitabine in the treatment of CMML.

Detailed Summary:
Sponsor: Fondazione Italiana Sindromi Mielodisplastiche Onlus

Current Primary Outcome: To assess the activity of decitabine in the treatment of CMML [ Time Frame: 24 months ]

Activity will be evaluated as percentage of patients achieving complete or partial remission according to the International Working Group response criteria in myelodysplasia


Original Primary Outcome: Same as current

Current Secondary Outcome: to assess the activity of decitabine in the treatment of CMML in terms of overall survival, time to leukemic transormation, response duration in terms of time to relapse after CR, PR, time to disease progression, ecc [ Time Frame: 24 months ]

Original Secondary Outcome: Same as current

Information By: Fondazione Italiana Sindromi Mielodisplastiche Onlus

Dates:
Date Received: December 1, 2010
Date Started: April 2010
Date Completion: June 2017
Last Updated: February 14, 2017
Last Verified: August 2016