Clinical Trial: Induction of Labor in Intrahepatic Cholestasis of Pregnancy
Study Status: Completed
Recruit Status: Completed
Study Type: Observational
Official Title: Induction of Labor in Intrahepatic Cholestasis of Pregnancy
Brief Summary: Induction of Labour in Intrahepatic Cholestasis of Pregnancy (ICP) has become a common procedure in management of ICP to avoid fetal complications. Surprisingly, this empirical approach has not been evaluated as to delivery complications and fetal outcome as yet. The investigators now examine weather ICP affects (i) delivery procedures chosen, in particular the incidence of caesarian section, (ii)fetal and maternal outcome in induced labor, and (iii)possible impact of bile acids and UDCA treatment in a retrospective cohort study based on approximately 5000 induced deliveries at Danderyd Hospital, Karolinska Institutet, Stockholm. The investigators analyze data on on previous deliveries, BMI, medical history and medical book data. Primary endpoint is the risk of caesarian section.
Detailed Summary:
Sponsor: Karolinska Institutet
Current Primary Outcome: Cesarean section [ Time Frame: 32 to 40 weeks ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Bleeding [ Time Frame: 32 to 40 weeks ]
- Abruptio placentae [ Time Frame: 32 to 40 weeks ]
- APGAR [ Time Frame: 32 to 40 weeks ]
Original Secondary Outcome: Same as current
Information By: Karolinska Institutet
Dates:
Date Received: June 23, 2011
Date Started: January 2000
Date Completion:
Last Updated: June 24, 2011
Last Verified: March 2010
