Clinical Trial: Partner Notification for Chlamydia in Primary Care
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Partner Notification for Chlamydia in Primary Care: Randomised Controlled Trial and Economic Evaluation
Brief Summary: The purpose of this study was to compare the effectiveness of partner notification by general practice nurses with referral to a specialist clinic for people with genital chlamydia diagnosed in a community setting. We hypothesised that referral to a specialist would be more effective in ensuring treatment of the sexual partners of infected people than the simpler nurse-led strategy.
Detailed Summary:
Partner notification (contact tracing) is essential to the control of sexually transmitted infections. Reports of new chlamydia infections have increased by 66% in the past five years. A National Chlamydia Screening Programme in England, and increasing primary care provision of sexual health care are part of the United Kingdom Government’s strategy for tackling increasing rates of sexually transmitted infections. New strategies for managing chlamydia in non-specialist settings are urgently required: genitourinary medicine clinics are failing to cope with their increasing workload; and 45% of cases detected in the chlamydia screening pilot studies were diagnosed in general practice.
Partner notification involves informing the sexual partners of someone with a sexually transmitted infection of the possibility of exposure, offering them diagnosis and treatment, and providing advice about preventing future infection. In the United Kingdom, this is usually done by specialist sexual health advisers in departments of genitourinary medicine. The effectiveness of partner notification in non-specialist settings in developed countries is not known. We conducted a randomised controlled trial to compare the effectiveness of practice nurse-led partner notification with referral to a genitourinary clinic for partner notification conducted by a specialist health adviser, and to compare the resources used by each strategy.
Comparisons: Partner notification at the time of receiving diagnosis and treatment by general practice nurses who received a one-day training course and ongoing support by telephone calls or visits from a specialist adviser in sexual health, compared with referral to a genitourinary medicine clinic for partner notification by a specialist adviser in sexual health.
Sponsor: University of Bristol
Current Primary Outcome:
- Percentage of index cases with at least one sexual partner treated
- Number of sexual partners per index case treated
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Number of sexual partners per index case elicited during sexual history taking
- Positive chlamydia test result six weeks after treatment
- Adherence to advice to abstain from sexual intercourse until both partners completed treatment
Original Secondary Outcome: Same as current
Information By: University of Bristol
Dates:
Date Received: May 31, 2005
Date Started: March 2001
Date Completion: December 2002
Last Updated: May 9, 2006
Last Verified: May 2005
