Clinical Trial: Impact on Management of the HEART Risk Score in Chest Pain Patients

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Cost-effectiveness Study of the HEART Score in the Management of Patients With Chest Pain Presenting in the Emergency Room

Brief Summary: Aim of this study is to quantify the impact of the use of the HEART risk score on patient outcome and on costs in patients with chest pain presenting at the emergency room, as compared to not using the score.

Detailed Summary: During 14 months, patients presenting with chest pain to the Emergency Department (ED) of participating hospitals will be included in the study. First, all hospitals will apply 'usual care' to all patients, i.e. risk assessment and subsequent management without application of the HEART score. Then, during a 14 month period, each 1,5 month 1 randomly allocated hospital will sequentially start to apply the HEART score in all chest pain patients (intervention period); during this intervention period patients with a HEART score 0-3 will not be admitted to the hospital (in accordance with the results of our validation studies), and patients with a HEART score above 3 will be treated according to current guidelines.
Sponsor: UMC Utrecht

Current Primary Outcome: MACE [ Time Frame: 6 weeks ]

occurrence of MACE (i.e. acute myocardial infarction (AMI), Percutaneous Coronary Intervention (PCI), Coronary Artery Bypass Grafting (CABG) or death) within 6 weeks after presentation


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • cost-effectiveness [ Time Frame: 3 months ]
    quality of life, costs and cost-effectiveness of the intervention compared with usual care.
  • MACE [ Time Frame: 3 months ]
    incidence of MACE and missed events


Original Secondary Outcome: Same as current

Information By: UMC Utrecht

Dates:
Date Received: December 20, 2012
Date Started: July 2013
Date Completion:
Last Updated: May 27, 2015
Last Verified: May 2015