Clinical Trial: The Impact of IV Acetaminophen on Pain After Appendectomy for Perforated Appendicitis
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Impact of IV Acetaminophen on Post-operative Pain After Laparoscopic Appendectomy for Perforated Appendicitis: A Prospective Randomized Trial
Brief Summary: The objective of this study is to evaluate two standard post-operative pain regimens routinely used after laparoscopic appendectomy for perforated appendicitis. The investigators hypothesize that the use of intravenous (IV) acetaminophen in addition to IV ketorolac with narcotic pain pump will decrease time to transition off patient/nurse controlled analgesia (PCA) to oral pain medications.
Detailed Summary:
To assess pain control, patient and family perception of pain control, time to return of bowel function defined as passage of first flatus (in days), doses of anti-emetic medications, doses of narcotic pain medications, time to toleration of regular diet (in days), narcotic associated adverse effects (nausea, emesis, respiratory depression, constipation), length of stay, and overall hospital cost in admission.
Post-hospitalization the investigators will assess complications including number and reasons for emergency visits and abscess formation, length of post-hospitalization analgesic use, length of post-hospitalization narcotic use, and time to return to school.
Sponsor: Children's Mercy Hospital Kansas City
Current Primary Outcome: Time until PCA discontinued after the operation [ Time Frame: 4 days ]
Original Primary Outcome: Same as current
Current Secondary Outcome: Duration of hospital stay [ Time Frame: 1 week ]
Original Secondary Outcome: Same as current
Information By: Children's Mercy Hospital Kansas City
Dates:
Date Received: January 18, 2016
Date Started: June 2014
Date Completion:
Last Updated: August 26, 2016
Last Verified: August 2016
