Clinical Trial: Infective Endocarditis in the Elderly

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational

Official Title: Infective Endocarditis in the Elderly: Description of the Geriatric Characteristics and Their Influence on Therapeutic Care and the Morbidity and Mortality at 3 Months (ELDERL-IE)

Brief Summary:

ELDERL-IE is a multicenter national prospective observational study.

The main objective is to describe geriatric characteristics (comorbidities, cognitive status, autonomy, nutritional status, balance and walking) in patients aged 75 years or older with infective endocarditis (IE).

The secondary objectives are to assess the impact of geriatric features on the medico - surgical care and on morbidity and mortality at 3 months after the end of the hospitalization, and to describe the initial clinical presentation and diagnostic modalities in the IE elderly.

Detailed Summary:

Population monitoring:

Clinical, therapeutic, biological, microbiological, echocardiographic and geriatric data are collected. (M-2/3 before inclusion; D-15 before inclusion; D0; M3; vital status at 1 year)

Sponsor: Central Hospital, Nancy, France

Current Primary Outcome: Change from baseline geriatric characteristics at 3 months [ Time Frame: 3 months after inclusion ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

• Three months mortality [ Time Frame: 3 months after inclusion ]
  Mortality rate at 3 months
• One year mortality [ Time Frame: 1 year after inclusion ]
  Mortality rate at 1 year
• Change from baseline geriatric characteristics at 3 months [ Time Frame: 3 months after inclusion ]
  Karnofsky'score
• Change from baseline geriatric characteristics at 3 months [ Time Frame: 3 months after inclusion ]
  Score MNA

Original Secondary Outcome: Same as current

Information By: Central Hospital, Nancy, France

Dates:
Date Received: August 25, 2016
Date Started: July 2014
Date Completion: October 2017
Last Updated: September 21, 2016
Last Verified: September 2016