Clinical Trial: MRI in Assessing Tumor Size in Women With Ductal Carcinoma In Situ
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Ductal Carcinoma in Situ: Protocol Evaluating the Assessment of Extension of Disease by MRI
Brief Summary:
RATIONALE: Diagnostic procedures, such as MRI, may help find ductal carcinoma in situ and find out how far the disease has spread.
PURPOSE: This clinical trial is studying how well MRI works in assessing tumor size in women with ductal carcinoma in situ.
Detailed Summary:
OBJECTIVES:
Primary
- Assess the contribution of MRI in accurately determining tumor size in women with ductal breast carcinoma in situ (DCIS).
Secondary
- Evaluate the sensitivity of MRI in detecting DCIS.
- Evaluate the contribution of mammography in accurately determining tumor size.
- Compare the contribution of MRI vs mammography in assessing tumor extension.
- Compare the contribution of MRI vs mammography in assessing dense breasts.
- Evaluate the morphology of DCIS by MRI.
- Evaluate the curve of dynamic MRI in assessing DCIS.
- Evaluate the impact of nuclear grade of DCIS by MRI.
- Evaluate the rate of revision surgery.
OUTLINE: Patients undergo clinical examination, mammography, ultrasound imaging, unilateral breast MRI, and tissue sampling.
Sponsor: Centre Antoine Lacassagne
Current Primary Outcome: Correlation of tumor extension by MRI with surgical histology [ Time Frame: up to 1 year ]
Original Primary Outcome: Correlation of tumor extension by MRI with surgical histology
Current Secondary Outcome:
Original Secondary Outcome:
Information By: Centre Antoine Lacassagne
Dates:
Date Received: April 1, 2009
Date Started: April 2007
Date Completion:
Last Updated: November 20, 2014
Last Verified: July 2009