Clinical Trial: MRI in Assessing Tumor Size in Women With Ductal Carcinoma In Situ

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Ductal Carcinoma in Situ: Protocol Evaluating the Assessment of Extension of Disease by MRI

Brief Summary:

RATIONALE: Diagnostic procedures, such as MRI, may help find ductal carcinoma in situ and find out how far the disease has spread.

PURPOSE: This clinical trial is studying how well MRI works in assessing tumor size in women with ductal carcinoma in situ.


Detailed Summary:

OBJECTIVES:

Primary

  • Assess the contribution of MRI in accurately determining tumor size in women with ductal breast carcinoma in situ (DCIS).

Secondary

  • Evaluate the sensitivity of MRI in detecting DCIS.
  • Evaluate the contribution of mammography in accurately determining tumor size.
  • Compare the contribution of MRI vs mammography in assessing tumor extension.
  • Compare the contribution of MRI vs mammography in assessing dense breasts.
  • Evaluate the morphology of DCIS by MRI.
  • Evaluate the curve of dynamic MRI in assessing DCIS.
  • Evaluate the impact of nuclear grade of DCIS by MRI.
  • Evaluate the rate of revision surgery.

OUTLINE: Patients undergo clinical examination, mammography, ultrasound imaging, unilateral breast MRI, and tissue sampling.


Sponsor: Centre Antoine Lacassagne

Current Primary Outcome: Correlation of tumor extension by MRI with surgical histology [ Time Frame: up to 1 year ]

Original Primary Outcome: Correlation of tumor extension by MRI with surgical histology

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Centre Antoine Lacassagne

Dates:
Date Received: April 1, 2009
Date Started: April 2007
Date Completion:
Last Updated: November 20, 2014
Last Verified: July 2009