Clinical Trial: Baclofen Treatment of Ataxia Telangiectasia

Study Status: Recruiting
Recruit Status: Unknown status
Study Type: Interventional

Official Title:

Brief Summary: This research is being done to find out if Baclofen, a medicine that is often used for the treatment of abnormal stiffness, might also be useful to treat some of the neurologic problems caused by ataxia telangiectasia (A-T). The investigators also want to find out if there are better ways to measure the problems of ataxia and abnormal eye movement for future studies of medication in ataxia telangiectasia.

Detailed Summary:
Sponsor: Johns Hopkins University

Current Primary Outcome: Improvement in the decay constant for velocity storage as assessed by quantitative video examination of eye movement during and after rotation. [ Time Frame: 3 months ]

Original Primary Outcome: Improvement in the decay constant for velocity storage as assessed by quantitative video examination of eye movement during and after rotation. [ Time Frame: months ]

Current Secondary Outcome: Other outcome measures include quantitative measurement of tremor, postural stability and a standard neurologic examination. [ Time Frame: 3 months ]

Original Secondary Outcome: Other outcome measures include quantitative measurement of tremor, postural stability and a standard neurologic examination. [ Time Frame: months ]

Information By: Johns Hopkins University

Dates:
Date Received: March 14, 2008
Date Started: April 2007
Date Completion: February 2011
Last Updated: March 3, 2011
Last Verified: December 2010