Clinical Trial: Molecular Genetic Screening and Identification of Congenital Arrhythmogenic Diseases
Study Status: Recruiting
Recruit Status: Unknown status
Study Type: Observational
Official Title: Molecular Genetic Screening and Identification of Congenital Arrhythmogenic Diseases
Brief Summary: The aim of this study is the identification of familial congenital arrhythmogenic disorders and their clinical follow-up.
Detailed Summary:
Molecular genetic screening in patients with:
- supraventricular
- ventricular arrhythmia
- syncopes of unknown origin and/or suspicion of an arrhythmogenic origin
- family members of patients with sudden cardiac death and aborted sudden cardiac death
Examination of patients includes routine testing like electrocardiogram (ECG), sequential ECGs, exercise testing, invasive electrophysiological stimulation, cardiac magnetic resonance imaging, intravenous drug challenge for identification/exclusion of eg Brugada syndrome. Examples are patients with Long QT Syndrome, Short QT Syndrome, Brugada Syndrome, familial atrial fibrillation, WPW-syndrome, arrhythmias due to familial hypertrophic cardiomyopathy or arrhythmogenic right ventricular dysplasia. Blood samples are taken for further molecular genetic screening.
Sponsor: Heidelberg University
Current Primary Outcome:
Original Primary Outcome:
Current Secondary Outcome:
Original Secondary Outcome:
Information By: Heidelberg University
Dates:
Date Received: September 14, 2005
Date Started: October 2003
Date Completion: December 2011
Last Updated: January 12, 2010
Last Verified: October 2003
