Clinical Trial: Ureteral Stents Versus Percutaneous Nephrostomy for Initial Urinary Drainage

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Ureteral Stents Versus Percutaneous Nephrostomy for Initial Urinary Drainage in Children With Obstructive Anuria and Acute Renal Failure Due to Ureteral Calculi: a Prospec

Brief Summary: To compare percutaneous nephrostomy (PCN) versus double J stent (JJ) as an initial urinary drainage in children

Detailed Summary: To compare percutaneous nephrostomy (PCN) versus double J stent (JJ) as an initial urinary drainage in children with obstructive calcular anuria and acute renal failure due to ureteric calculi to identify selection criteria for initial urinary drainage method to improve drainage, to decrease complications and to facilitate subsequent definitive clearance of stones as this comparison is lacking in literature
Sponsor: Cairo University

Current Primary Outcome:

  • Period to Return to Normal Creatinine [ Time Frame: 1 week ]

    period required for normalization of serum creatinine after initial urinary drainage using percutaneous nephrostomy or ureteric stent in children with obstructive calcular anuria and Acute Renal Failure

    serum creatinine was compared to normal values in matched healthy children

  • Complications of Each Drainage Method [ Time Frame: 1 week ]

    complications of initial urinary drainage using percutaneous nephrostomy or ureteric stent in children with Obstructive Anuria and Acute Renal Failure (mucosal complications, failure of insertion, slippage, fever and infection, hematuria, leakage)

    complications were calculated per 45 ureterorenal units in PCN group and 90 ureterorenal units in Double J group



Original Primary Outcome:

  • Period to Return to Normal Creatinine [ Time Frame: 1 week ]
    period required for normalization of serum creatinine after initial urinary drainage using percutaneous nephrostomy or ureteric stent in children with obstructive calcular anuria and Acute Renal Failure
  • Complications of Each Drainage Method [ Time Frame: 1 week ]
    complications of initial urinary drainage using percutaneous nephrostomy or ureteric stent in children with Obstructive Anuria and Acute Renal Failure (mucosal complications, failure of insertion, slippage, fever and infection, hematuria, leakage)


Current Secondary Outcome: The Number of Subsequent Interventions Needed for Clearance of Stones . [ Time Frame: 6 months ]

The number of subsequent interventions needed for clearance of stones after normalization of serum creatinine in relation to initial urinary drainage method using percutaneous nephrostomy or ureteric stent in children with Obstructive Anuria and Acute Renal Failure


Original Secondary Outcome: Same as current

Information By: Cairo University

Dates:
Date Received: February 3, 2014
Date Started: March 2010
Date Completion:
Last Updated: March 19, 2014
Last Verified: March 2014