Clinical Trial: Delayed or Direct Ureteroscopy in the Treatment of Pediatric Calcular Anuria

Study Status: Recruiting
Recruit Status: Unknown status
Study Type: Interventional

Official Title: Staged Ureteroscopy After Initial Urinary Drainage Versus Direct Ureteroscopy in the Treatment of Pediatric Obstructive Calcular Anuria

Brief Summary: To compare staged ureteroscopy following initial urinary drainage versus direct ureteroscopy without initial urinary drainage in the treatment of obstructive calcular anuria with acute renal failure in children.

Detailed Summary: To compare staged ureteroscopy following initial urinary drainage and stabilization of renal functions using percutaneous nephrostomy or double J stent versus direct ureteroscopy without initial urinary drainage in the treatment of obstructive calcular anuria with acute renal failure due to ureteric calculi in children.
Sponsor: Cairo University

Current Primary Outcome:

  • Return to normal creatinine [ Time Frame: 1 week ]
    period for return to normal creatinine in both groups
  • stone free status [ Time Frame: 1 week ]
    success in removal of ureteric stones using ureteroscopy
  • operative and early post operative complications [ Time Frame: 1 week ]
    Hematuria, Extravasation (perforation), mucosal complications, stone migration, failure of ureteric access, fever


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • ureteric stricture [ Time Frame: 6 months ]
    occurrence of ureteric stricture as a delayed complication
  • period to reach stone free status bilaterally [ Time Frame: 6 months ]
    period to reach stone free status bilaterally after the treatment of the contralateral side
  • number of times of exposure to general anesthesia [ Time Frame: 6 months ]
    number of times of exposure to general anesthesia during successive interventions to clear stones bilaterally


Original Secondary Outcome: Same as current

Information By: Cairo University

Dates:
Date Received: May 13, 2014
Date Started: June 2014
Date Completion: December 2015
Last Updated: February 2, 2015
Last Verified: February 2015