Clinical Trial: Delayed or Direct Ureteroscopy in the Treatment of Pediatric Calcular Anuria
Study Status: Recruiting
Recruit Status: Unknown status
Study Type: Interventional
Official Title: Staged Ureteroscopy After Initial Urinary Drainage Versus Direct Ureteroscopy in the Treatment of Pediatric Obstructive Calcular Anuria
Brief Summary: To compare staged ureteroscopy following initial urinary drainage versus direct ureteroscopy without initial urinary drainage in the treatment of obstructive calcular anuria with acute renal failure in children.
Detailed Summary: To compare staged ureteroscopy following initial urinary drainage and stabilization of renal functions using percutaneous nephrostomy or double J stent versus direct ureteroscopy without initial urinary drainage in the treatment of obstructive calcular anuria with acute renal failure due to ureteric calculi in children.
Sponsor: Cairo University
Current Primary Outcome:
- Return to normal creatinine [ Time Frame: 1 week ]period for return to normal creatinine in both groups
- stone free status [ Time Frame: 1 week ]success in removal of ureteric stones using ureteroscopy
- operative and early post operative complications [ Time Frame: 1 week ]Hematuria, Extravasation (perforation), mucosal complications, stone migration, failure of ureteric access, fever
Original Primary Outcome: Same as current
Current Secondary Outcome:
- ureteric stricture [ Time Frame: 6 months ]occurrence of ureteric stricture as a delayed complication
- period to reach stone free status bilaterally [ Time Frame: 6 months ]period to reach stone free status bilaterally after the treatment of the contralateral side
- number of times of exposure to general anesthesia [ Time Frame: 6 months ]number of times of exposure to general anesthesia during successive interventions to clear stones bilaterally
Original Secondary Outcome: Same as current
Information By: Cairo University
Dates:
Date Received: May 13, 2014
Date Started: June 2014
Date Completion: December 2015
Last Updated: February 2, 2015
Last Verified: February 2015