Clinical Trial: The Impact of Indocyanine Green-enhanced Fluorescence Imaging on Bowel Transection in Left-sided Colorectal Resection

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: A Prospective Study to Investigate the Impact of Using Indocyanine Green-enhanced Fluorescence Imaging on the Location of Bowel Transection in Patients Undergoing Left-sided Colorectal Resection

Brief Summary: The aim of this study was to evaluate the impact of fluorescence imaging on the location of colorectal transection lines based on evaluation of perfusion with indocyanine green, how it's going to affect surgical planning and its possible benefits in reducing anastomotic leakage.

Detailed Summary: During surgery, the line of intended bowel transection would be determined by the surgeon. Then the anesthesiologist will administer a bolus of 5mg ICG intravenously (2.5mg/ml, 2ml), followed by 10ml normal saline flush. The perfusion of colon will be assessed via fluorescence angiography. The actual bowel transection, after ICG fluorescence study, would be compared with the intended bowel transection site. The difference in terms of distance and either more proximal or distal is recorded. Then bowel anastomosis is completed in the usual manner.
Sponsor: The University of Hong Kong

Current Primary Outcome: Number of patients with operative decisions changed after the use of ICG enhanced fluorescence imaging [ Time Frame: intraoperative ]

Original Primary Outcome: Same as current

Current Secondary Outcome: Anastomotic leak [ Time Frame: up to 2 weeks after operation ]

Original Secondary Outcome: Same as current

Information By: The University of Hong Kong

Dates:
Date Received: January 21, 2016
Date Started: January 2016
Date Completion: December 2017
Last Updated: January 29, 2016
Last Verified: January 2016