Clinical Trial: Pathogenesis of Functional Hypothalamic Amenorrhea

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Pathogenesis of Functional Hypothalamic Amenorrhea

Brief Summary: This is a randomized pilot study of the use of cognitive behavior therapy versus observation to treat functional hypothalamic amenorrhea, often termed stress-induced anovulation.

Detailed Summary: The study enrollment was completed in 2003. The study results are being analyzed.
Sponsor: University of Pittsburgh

Current Primary Outcome: ovarian function [ Time Frame: Change before and after 20 weeks of CBT or observation ]

The change in ovarian function was assessed by comparing ovarian function before and after 20 weeks of CBT or observation using menses and serial estradiol and progesterone level as indices of ovarian function


Original Primary Outcome: Same as current

Current Secondary Outcome: metabolism [ Time Frame: Change before and after 20 weeks of CBT or observation ]

The change in metabolism was assessed by measuring levels of cortisol, TSH, T4, free T4, T3, free T3, leptin in blood and by measuring weight before and after 20 weeks of CBT or observation


Original Secondary Outcome: Same as current

Information By: University of Pittsburgh

Dates:
Date Received: August 14, 2012
Date Started: November 1997
Date Completion:
Last Updated: August 24, 2012
Last Verified: August 2012