Clinical Trial: Microbioma in Sputa From COPD With Alpha-1 Antitrypsin Deficiency

Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Observational

Official Title: Microbioma in Sputa From COPD With Alpha-1 Antitrypsin Deficiency

Brief Summary: In the context of the increasing evidence of the pathogenetic role of microbiome in COPD, our aim is to determine the total and specific bacterial and viral load in sputa from patients with COPD due to AATD and to correlate these findings with cellular, biochemical and immunological characteristics of sputa. These quantitative data obtained from sputum will be analyzed in the context of the clinical and physiological parameters of the patients.

Detailed Summary:
Sponsor: Fondazione Salvatore Maugeri

Current Primary Outcome: composition of microbioma in sputa [ Time Frame: 2 years ]

Original Primary Outcome: Same as current

Current Secondary Outcome: correlation with clinical and physiological parameters [ Time Frame: 2 years ]

Original Secondary Outcome: Same as current

Information By: Fondazione Salvatore Maugeri

Dates:
Date Received: September 9, 2015
Date Started: September 2015
Date Completion: October 2017
Last Updated: September 9, 2015
Last Verified: September 2015