Clinical Trial: Safety Study of Continuous Positive Airway Pressure Via a Nasal Mask
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Effect of Continuous Positive Airway Pressure Ventilation Through Nasal Mask on Upper Airway Patency During Induction of Anesthesia
Brief Summary: Upper airway obstruction (UAO) is common complication during induction of general anesthesia. The mechanism of UAO during anesthesia has not been well understood. Posterior displacement of soft palate are believed to be the primary contributing factors. The mechanism of UAO during anesthesia share many similarities with obstructive sleep apnea (OSA). Since nasal continuous positive airway pressure (nCPAP) can maintain the airway patent in patients with OSA, the investigators hypothesize that nCPAP during induction of anesthesia will reduce the incidence and severity of UAO.
Detailed Summary:
Sponsor: Massachusetts General Hospital
Current Primary Outcome: expired tidal volume [ Time Frame: Average of one minute after anesthesia induction ]
Original Primary Outcome: Same as current
Current Secondary Outcome: volume of CO2 [ Time Frame: Average of one minute after anesthesia induction ]
Original Secondary Outcome: Same as current
Information By: Massachusetts General Hospital
Dates:
Date Received: January 12, 2012
Date Started: October 2011
Date Completion:
Last Updated: January 15, 2017
Last Verified: January 2017