Clinical Trial: Efficacy of Intravenous (IV) Paracetamol for Treatment of Acute Pain

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Comparison of IV Paracetamol With Intravenous Morphine Sulfate in Treatment of Acute Pain Due to Limb Trauma

Brief Summary: The purpose of this study is to determine whether Iv paracetamol is as effective as Iv Morphine sulfate on control of the acute pain in Patient with limb trauma.

Detailed Summary:

Limb trauma is a painful condition that requires urgent analgesic treatment . Intravenous Opioids and NSAIDs are used extensively to control pain; both of them are with side effects. Paracetamol is a safe and effective analgesic that is used by oral or rectal routs for pain control, and in therapeutic doses has less side effects than Morphine and NSAIDs, and approved as a safe and effective analgesic in emergency department.

recently Iv Paracetamol has become available in European countries and also in Iran.

efficacy and safety of IV Paracetamol has been studied in post operation conditions and asserted but in emergency setting it has been studied only in renal colic situation.

Therefore, the investigators want to study the efficacy of IV Paracetamol in limb trauma and compare it with Iv Morphine sulfate.

Sponsor: Tehran University of Medical Sciences

Current Primary Outcome: Change in pain severity/score [ Time Frame: after 30 minutes ]

Original Primary Outcome: Same as current

Current Secondary Outcome: Need for rescue analgesia [ Time Frame: After 30 minutes ]

Original Secondary Outcome: Same as current

Information By: Tehran University of Medical Sciences

Dates:
Date Received: November 2, 2011
Date Started: November 2011
Date Completion:
Last Updated: December 6, 2012
Last Verified: December 2012