Clinical Trial: Clinical Values of Automated Electronic Alert for Acute Kidney Injury

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Clinical Values of Automated Electronic Alert for Acute Kidney injury-a Prospective ,Randomly Controlled Cohort Study

Brief Summary: Acute kidney injury (AKI) is common, serious and expensive.It is associated with significant mortality, morbidity and increased length of hospital stay.To improve clinical outcomes of AKI by early detection and timely referral to the renal,the investigators developed an electronic alert system which identifies all cases of AKI occurring in patients over 18 years.The system was also designed to collect data on AKI incidence one of the biggest tertiary hospital in China.

Detailed Summary:

A prospective, randomly controlled cohort study will be conducted agmong the patients with AKI who are detected by the use of AKI sniffer. The investigators chose to assess all inpatient serum creatinine results using a combination of "KDIGO" criteria.

The investigators randomly divided the patients into two groups:

  1. Usual care : patients will receive standard clinical care by the primary physicians
  2. AKI alert : an AKI alert will be sent to the the doctor in charge. Our team of kidney experts would give a suggestion if the the doctor in charge issue consultation applications.

Sponsor: XinLing Liang

Current Primary Outcome:

  • Adverse events during hospitalization [ Time Frame: from start of AKI to discharge,up to 4 weeks ]
    cardiac shock/ need for intensive care/ cardiopulmonary resuscitation/ cardiac death/ death
  • Incidence of cardiovascular disease and its occurrence time followed up for 1 years [ Time Frame: One year after discharge ]
    heart failure/ acute coronary syndrome/ readmission/cardiac readmission/ cardiovascular intervention or surgery
  • The AKI outcome and its occurrence time followed up for 1 years [ Time Frame: One year after discharge ]
    AKI recovery/stop renal replacement therapy
  • AKI recovery/stop renal replacement therapy [ Time Frame: from start of AKI to discharge,up to 4 weeks ]
    Glomerular filtration rate decreased/ new occurrence proteinuria/ original proteinuria aggravation


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Proportion of nephrology referral [ Time Frame: from start of AKI to discharge,up to 4 weeks ]
  • Diagnostic rate of AKI at discharge [ Time Frame: from start of AKI to discharge,up to 4 weeks ]
  • Follow-up rate after discharge [ Time Frame: One year after discharge ]


Original Secondary Outcome: Same as current

Information By: Guangdong General Hospital

Dates:
Date Received: May 23, 2016
Date Started: March 2016
Date Completion: March 2019
Last Updated: February 6, 2017
Last Verified: February 2017