Clinical Trial: Goal Directed Therapy for Acute Kidney Injury in Critical Ill Patients

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Goal Directed Therapy in the Early Phase of Acute Kidney Injury in Critical Ill Patients

Brief Summary:

Acute kidney injury (AKI) is a frequent complication in critically ill patients admitted to intensive care unit (ICU) and it is associated with increased morbimortality.

There is evidence that perioperative hemodynamic optimization decreases the incidence of AKI in the post operative phase in high-risk patients. We aimed to evaluate if the use of a goal-directed therapy to increase oxygen delivery in the early phase of acute kidney injury can decrease the prevalence of patients with acute renal failure.

Detailed Summary: Randomized, controlled, multicenter study.The intervention group was monitored with Flo Trac/Vigileo and optimized with fluid challenges, dobutamine and blood transfusion, if necessary, to maintain a IDO² ≥600ml/min/m² during 8h. The control group was treated according to the discretion of the attending physician.
Sponsor: Barretos Cancer Hospital

Current Primary Outcome: acute kidney injury [ Time Frame: 2 months ]

Original Primary Outcome: Same as current

Current Secondary Outcome: death [ Time Frame: 2 months ]

Original Secondary Outcome: Same as current

Information By: Barretos Cancer Hospital

Dates:
Date Received: April 8, 2015
Date Started: June 2010
Date Completion:
Last Updated: April 8, 2015
Last Verified: March 2015