Clinical Trial: Habitual Abortion Study: Oral Dydrogesterone Treatment During Pregnancy in Women With Recurrent Miscarriage

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Oral Dydrogesterone Treatment During the First Trimester of Pregnancy in Women With Recurrent Miscarriage: A Double-Blind, Prospectively Randomized, Placebo-Controlled, Pa

Brief Summary: The purpose of this clinical study is to demonstrate the shift from inflammatory cytokines to non-inflammatory cytokines in women suffering from habitual abortion treated with dydrogesterone (Duphaston).

Detailed Summary:
Sponsor: Abbott Products

Current Primary Outcome: Cytokine ratio IFN/IL-10 [ Time Frame: 14 weeks treatment after diagnosed pregnancy (week of gestation 4 to 18) ]

Original Primary Outcome:

Current Secondary Outcome: Exploratory analysis of pregnancy outcome by monitoring biochemical and clinical pregnancy parameters, weekly evaluation of serum progesterone [ Time Frame: First trimester of pregnancy ]

Original Secondary Outcome:

Information By: Abbott

Dates:
Date Received: September 11, 2005
Date Started: September 2003
Date Completion:
Last Updated: August 25, 2011
Last Verified: August 2011