Clinical Trial: Augmented Pulse Pressure Variation to Predict Fluid Responsiveness in Open Laparotomy
Study Status: Completed
Recruit Status: Completed
Study Type: Observational
Official Title: Pulse Pressure Variation With Augmented Ventilation to Predict Fluid Responsiveness in the Patients Undergoing Open Laparotomy Surgery
Brief Summary: Pulse pressure variation (PPV) is a well-known and widely used dynamic preload indicator based on heart-lung interaction to predict fluid responsiveness. Generally, patients are considered to be fluid-responsive when the PPV value larger than 11-13%. However, several previous researches demonstrated that there is a zone of uncertainty (grey zone) in PPV. To predict fluid-responsiveness accurately in the patients with PPV within grey zone (9-13%), the investigators would evaluate the augmented PPV using augmented ventilation.
Detailed Summary:
Sponsor: Samsung Medical Center
Current Primary Outcome: Augmented PPV (Pulse Pressure Variation) to predict fluid responsiveness [ Time Frame: within 2 min from augmented ventilation ]
Original Primary Outcome: Same as current
Current Secondary Outcome: Conventional baseline PPV to predict fluid responsiveness [ Time Frame: when patients PPV in grey zone, before augmented ventilation ]
Original Secondary Outcome: Same as current
Information By: Samsung Medical Center
Dates:
Date Received: October 20, 2015
Date Started: September 2015
Date Completion:
Last Updated: March 2, 2016
Last Verified: March 2016